Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase (EC220.127.116.11, SHIP1, SHIP2, SHIP, p150Ship) is an enzyme with system name 1-phosphatidyl-1D-myo-inositol-3,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction
This enzyme hydroylses 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2.
PC/GEOS was first created by Berkeley Softworks, who later became GeoWorks Corporation. Version 4.0 was developed in 2001 by Breadbox Computer Company, LLC, and named Breadbox Ensemble.
PC/GEOS should not be confused with the 8-bit GEOS product from the same company, which runs on the Commodore 64 and other computers using MOS 6502-compatible microprocessors.
In 1990, GeoWorks released GEOS for IBM PC compatible systems, PC/GEOS. Also called GeoWorks Ensemble, it was incompatible with the earlier 8-bit versions of GEOS for Commodore and Apple II computers, but provided numerous enhancements, including scalable fonts and multitasking even on XT and AT-class PC clones. GeoWorks saw a market opportunity to provide a graphical user interface for the 16 million older model PCs that were unable to run Microsoft Windows 2.x.
A geo or gio (/ɡjoʊ/GYOH, from Old Norse gjá) is an inlet, a gully or a narrow and deep cleft in the face of a cliff. Geos are common on the coastline of the Shetland and Orkney islands. They are created by the wave driven erosion of cliffs along faults and bedding planes in the rock. Geos may have sea caves at their heads. Such sea caves may collapse, extending the geo, or leaving depressions inland from the geo.